What is The Mechanism of Action of Ibogaine?

Ibogaine, a naturally occurring alkaloid found in the African shrub <i>Tabernanthe iboga</i>, has garnered attention for its potential in treating substance addictions. Its mechanism of action is multifaceted and not fully understood. It's believed to act on various neurotransmitter systems, including the serotonin, dopamine, and opioid systems. By modulating these pathways, Ibogaine can influence craving and withdrawal symptoms. Additionally, its psychoactive properties, which can induce introspective and vivid dream-like experiences, are thought to contribute to its potential therapeutic effects. As research continues, a clearer understanding of Ibogaine's mechanism will be pivotal in optimizing its use in addiction treatment.